Publications

Peer Reviewed Publications

I have co-authored 21 peer reviewed publications and 2 submitted manuscripts. These publications span from original research to case reports and review articles. They pertain to research fields of AI in medicine, image analysis in radiology, medical devices, ophthalmology, and molecular imaging.

AI in Medicine and Radiology

  1. Valliani AA, Link KE, Costa AB, Kwon YJ, Lui YW, Kondziolka D, Oermann EK.
    "Medical Federated Learning Models Trained on Real-world Data Are Vulnerable to Attack and Human Error,"
    Sci Adv, 2021; Pub Status: Submitted.

  2. Valliani AA, Kwon YJ, Martini ML, Wang C, Kondziolka D, Chen VJ, Wang W, Costa AB, Oermann EK.
    "Deploying Deep Learning Models on Unseen Medical Imaging Using Adversarial Domain Adaptation,"
    Nat Biomed Eng, 2021. Pub Status: Revisions Submitted.

  3. The EXAM Consortium. Institutional team contributors: Costa AB, Kwon YJ, Oermann EK, Glicksberg BS
    "Federated Learning Used for Predicting Outcomes in SARS-COV-2 Patients,"
    Nature Medicine, 2021; Online ahead of print. Cited in PubMed; PMID: 34526699. Pub Status: Published.

  4. Kwon YJ, Toussie D, Finkelstein M, Cedillo MA, Maron SZ, Manna S, Voutsinas N, Eber C, Jacobi A, Bernheim A, Gupta YS, Chung MS, Fayad ZA, Glicksberg BS, Oermann EK, Costa AB.
    "Combining Initial Radiographs and Clinical Variables Improves Deep Learning Prognostication of Patients with COVID-19 from the Emergency Department,"
    Radiol Artif Intell, 2020; 3(2). Cited in PubMed; PMID: 33928257. Pub Status: Published.

  5. Vaid A, Jaladanki S, Xu J, Teng S, Kumar A, Lee S, Somani S, Paranjpe I, De Freitas JK, Wanyan T, Johnson KW, Bicak M, Klang E, Kwon YJ, Costa A, Zhao S, Miotto R, Charney AW, Bottinger E, Fayad ZA, Nadkarni GN, Wang F, Glicksberg BS.
    "Federated Learning of Electronic Health Records Improves Mortality Prediction in Patients Hospitalized with COVID-19,"
    JMIR Med Inform, 2020; 9(1):e24207. Cited in Pubmed; PMID: 33400679. Pub Status: Published.

  6. Kwon YJ, Toussie D, Azour L, Concepcion J, Eber C, Reina GA, Tang P, Doshi AH, Oermann EK, Costa AB.
    "Appropriate Evaluation of Diagnostic Utility of Machine Learning Algorithm Generated Images,"
    Proc Mach Learn Res, 2020; 136:179-193. Pub Status: Published.

  7. Kwon YJ, Toussie D, Reina GA, Tang P, Doshi AH, Oermann EK, Costa AB.
    "Multi-Level Vector Quantized Variational AutoEncoder as a Lightweight, Generalizable Medical Imaging Compression Algorithm,"
    Medical Imaging Meets NeurIPS, 2020; 27. Pub Status: Published.


Image Analysis in Radiology

  1. Mahmoudi K, Kwon YJ, Kihira S, Goldstein Y, Platt S, Garvey KL, Belani P, Rigney B, Naidich T, Costa AB, Doshi AH.
    "Body Mass Index Correlates with Skin to Spinal Canal Distance: A Large Retrospective Single-Center Study,"
    J Neuroimaging, 2020; 30(6):896-900. Cited in Pubmed; PMID: 32639650. Pub Status: Published.

  2. Lau KC, Kwon YJ, Aziz MK, Maidment AD.
    "Estimating breast thickness for dual-energy subtraction in contrast-enhanced digital mammography using calibration phantoms,"
    The International Society for Optics and Photonics, 2016; Paper 9783-11. doi: https://doi.org/10.1117/12.2214748. Pub Status: Published.

  3. Vent TL, Acciavatti RJ, Kwon YJ, Maidment AD.
    "Quantification of resolution in multiplanar reconstructions for digital breast tomosynthesis,"
    The International Society for Optics and Photonics, 2016; Paper 9783-1. doi: https://doi.org/10.1117/12.2216260. Pub Status: Published.


Medical Devices

  1. Grinberg D, Le MQ, Kwon YJ, Fernandez MA, Audigier D, Ganet F, Capsal JF, Obadia JF, Cottinet PJ.
    "Mitral Valve Repair Based on Intraoperative Objective Measurement,"
    Sci Rep, 2019; 18;9(1):4677. Cited in PubMed; PMID: 30886234. Pub Status: Published.

  2. Grinberg D, Pozzi M, Bordet M, Nouhou KA, Kwon YJ, Obadia JF, Vola M.
    "Minithoracotomy and Beating Heart Strategy for Mitral Surgery in Secondary Mitral Regurgitation,"
    Thorac Cardiovasc Surg, 2019; 68(6):462-469. Cited in PubMed; PMID: 31242521. Pub Status: Published.


Ophthalmology

  1. Kwon YJ, Allen JL, Liu GT, McCormack SE.
    "Presumed pseudotumor cerebri syndrome after withdrawal of inhaled glucocorticoids,"
    Pediatrics, 2016; 137(6). Cited in PubMed; PMID: 27244842. Pub Status: Published.

  2. Sheldon CA, Kwon YJ, Liu GT, McCormack SE.
    "An integrated mechanism of pediatric pseudotumor cerebri syndrome: Evidence of bioenergetic and hormonal regulation of cerebrospinal fluid dynamics,"
    Pediatr Res, 2015; 77(2): 282-9. Cited in PubMed; PMID: 25420176. Pub Status: Published.


Molecular Imaging in Metabolism

  1. Guha S, Mathew ND, Konkwo C, Ostrovsky J, Kwon YJ, Polyak E, Seiler C, Bennett M, Xiao R, Zhang Z, Nakamaru-Ogiso E, Falk MJ.
    "Combinatorial glucose, nicotinic acid, and N-acetylcysteine therapy has synergistic effect in preclinical C. elegans and zebrafish models of mitochondrial complex I disease,"
    Hum Mol Genet, 2021; 30(7):536-551. Cited in PubMed; PMID: 33640978. Pub Status: Published.

  2. Guha S, Konkwo C, Lavorato M, Mathew ND, Peng M, Ostrovsky J, Kwon YJ, Polyak E, Lightfoot R, Seiler C, Xiao R, Bennett M, Zhang Z, Nakamaru-Ogiso E, Falk MJ.
    "Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease,"
    Hum Mol Genet, 2019; 28(11):1837–1852. Cited in PubMed; PMID: 30668749. Pub Status: Published.

  3. Kwon YJ, Guha S, Tuluc F, Falk MJ.
    "High-Throughput Biosorter Quantification of Relative Mitochondrial Mass and Membrane Potential in living C. elegans,"
    Mitochondrion, 2018; 40:42-50. Cited in PubMed; PMID: 28986305. Pub Status: Published.

  4. Polyak E, Ostrovsky J, Peng M, Dingley SD, Tsukikawa M, Kwon YJ, McCormack SE, Bennett M, Xiao R, Seiler C, Zhang Z, Falk MJ.
    "N-acetylcysteine and vitamin E rescue animal longevity and cellular oxidative stress in pre-clinical models of mitochondrial complex I disease,"
    Mol Genet Metab, 2018; 123(4):449-462. Cited in PubMed; PMID: 29526616. Pub Status: Published.

  5. Kong J, Peng M, Ostrovsky J, Kwon YJ, Oretsky O, McCormick EM, He M, Argon Y, Falk MJ.
    "Mitochondrial function requires NGLY1,"
    Mitochondrion, 2018; 38:6-16. Cited in PubMed; PMID: 28750948. Pub Status: Published.

  6. Kwon YJ, Falk MJ, Bennett M.
    "Flunarizine Rescues Reduced Lifespan in CLN3 Triple Knock-Out Caenorhabditis elegans Model of Batten Disease,"
    J Inherit Metab Dis, 2017; 40(2):291-296. Cited in PubMed; PMID: 27766444. Pub Status: Published.

  7. Peng M, Ostrovsky J, Kwon YJ, Polyak E, Licata J, Tsukikawa M, Marty E, Thomas J, Felix CA, Xiao R, Zhang Z, Gasser D, Argon Y, Falk MJ.
    "Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease,"
    Hum Mol Genet, 2015; 24(17): 4829-47. Cited in PubMed; PMID: 26041819. Pub Status: Published.

  8. McCormack S, Polyak E, Ostrovsky J, Dingley S, Rao M, Kwon YJ, Xiao R, Zhang Z, Nakamaru-Ogiso E, Falk MJ.
    "Pharmacologic targeting of disordered NAD+ metabolism improves longevity in Caenorhabditis elegans mitochondrialcomplex I mutants,"
    Mitochondrion, 2015; 22: 45-59. Cited in PubMed; PMID: 25744875. Pub Status: Published.

  9. Dingley S, Polyak E, Ostrovsky J, Srinivasan S, Lee I, Rosenfeld A, Tsukikawa M, Xiao R, Selak M, Coon J, Hebert A, Grimsrud P, Kwon YJ, Pagliarini D, Gai X, Schurr T, Huttemann M, Nakamaru-Ogiso E, Falk M.
    "Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans,"
    J Mol Biol, 2014; 426(11):2199-216. Cited in PubMed; PMID: 24534730. Pub Status: Published.

Presentations

I have presented at NeurIPS, RSNA, SIR, and other annual meetings in AI, radiology, and metabolic research.

Oral Presentations

  1. Mahmoudi K, Kwon YJ, Shingo K, Puneet B, Naidich T, Costa A, Doshi A. (April, 2021).
    "Body Mass Index Correlates with Skin to Spinal Canal Distance: A Large Retrospective Single-Center Study."
    Oral Presentation submitted to: American Roentgen Ray Society (ARRS) Annual Meeting 2021; San Diego, CA, USA.

  2. Marinelli B, Kwon YJ, Maron S, Radell J, Cooke P, Sharma H, Dreher N, Roig J, Patel R, Fischman A, Ranade M, Bishay V, Nowakowski SF, Kim E, Oermann EK, Lookstein R, Titano J. (April, 2020).
    "Fast, Automated Intra-abdominal Hemorrhage Detection on CT Angiography Prior to Embolization Using Convolutional Neural Networks."
    Oral Presentation accepted at: Society of Interventional Radiology 45th Annual Scientific Meeting; Seattle, WA, USA. Cancelled due to COVID-19.

  3. Marinelli B, Stocker D, Charles D, Pasik S, Kwon YJ, Patel R, Fischman A, Bishay V, Ranade M, Nowakowski SF, Lookstein R, Taouli B, Kim E. (December, 2019).
    "Early Tumor Viability Prediction Following Y90 Radioembolization Segmentectomy for Hepatocellular Carcinoma Using Automated 3D Tumor Sub-Volume Segmentation and Texture Analysis."
    Oral Presentation presented at: 105th Scientific Assembly and Annual Meeting, Radiological Society of North America; Chicago, IL, USA.
    https://rsna2019.rsna.org/program/index.cfm Abstract SSC06-06.

  4. Kwon YJ, Oermann EK, Costa AB. (December, 2018).
    "Application of Convolutional Adversarial Autoencoder with Auxiliary Task."
    Oral Presentation presented at: Digital Neuro Symposium: Artificial Intelligence, Advanced Digital Technologies, and Device Development in Neurosurgery; New York, NY, USA.
    https://mssm.cloud-cme.com/assets/MSSM/data/DigitalNeuroSympsium.pdf

  5. Kwon YJ, Gruener J, Cristescu M, Goldman D, Fischman A, Bishay V, Ranade M, Patel R, Nowakowski FS, Lookstein R, Kim E. (May, 2018).
    "TACE with 70-150 um Radiopaque Drug-Eluting Beads in Treatment Naive HCC: Single Center Short-term Safety and Efficacy."
    Oral Presentation presented at: 12th Annual Global Embolization Symposium and Technologies Meeting; Miami Beach, FL, USA.

  6. Maidment A, Acciavatti RJ, Vent TL, Kwon YJ, Ng S, Kuo J, Ringer PA, Licata J, Narayan T, Zhang D, Maidment T, Higginbotham D. (November, 2016).
    "Construction of a Prototype Digital Breast Tomosynthesis System with Superior Spatial Resolution."
    Oral Presentation presented at: 102nd Scientific Assembly and Annual Meeting, Radiological Society of North America; Chicago, IL, USA.
    http://rsna2016.rsna.org/program/index.cfm Abstract SSC14-03.

  7. Kwon YJ, Falk MJ, Bennett M. (April, 2016).
    "Flunarizine rescues short lifespan of CLN3 knockout Caenorhabditis elegans model of Batten disease."
    Oral Presentation presented at: Society for Inherited Metabolic Disorders 38th Annual Meeting; Ponte Vedra Beach, FL, USA.
    https://www.simd.org/Meetings/SIMD2016/Program.asp

  8. Lau K, Aziz M, Kwon YJ, Maidment A. (November, 2015).
    "Determinants of the Accuracy of the Quantification of Glandularity and Iodine Uptake in Contrast-Enhanced Digital Mammography."
    Oral Presentation presented at: 101st Scientific Assembly and Annual Meeting, Radiological Society of North America; Chicago, IL, USA.
    https://rsna2015.rsna.org/program/details/?publicid=rc225 RC225-03

  9. He M, Peng M, Li X, Ostrovsky J, Kwon YJ, Raihan M, Davids M, Boerkoel C, McCormick E, Suzuki T, Argon Y, Falk MJ. (March, 2015).
    NGLY1 deficiency lies in the crosshairs of CDG and Mitochondrial Diseases.
    Oral Presentation presented at: Society for Inherited Metabolic Disorders 37th Annual Meeting; Salt Lake City, UT, USA.
    https://www.simd.org/Meetings/SIMD2015/Program.asp

Poster Presentations

  1. Kwon YJ, Toussie D, Azour L, Concepcion J, Eber C, Reina GA, Tang P, Doshi AH, Oermann EK, Costa AB. (December 2020).
    "Appropriate Evaluation of Diagnostic Utility of Machine Learning Algorithm Generated Images."
    Poster Presentation at: Machine Learning for Health at NeurIPS; Virtual meeting.
    https://ml4health.github.io/2020/pages/papers.html

  2. Kwon YJ, Toussie D, Reina GA, Tang P, Doshi AH, Oermann EK, Costa AB. (December 2020).
    "Autoencoder Image Compression Algorithm for Reduction of Resource Requirements."
    Poster Presentation at: Medical Imaging Meets NeurIPS; Virtual meeting.
    https://slideslive.com/38943127/autoencoder-image-compression-algorithm-for-reduction-of-resource-requirements

  3. Yoon J, Kwon YJ, Park LS, Li H, Le RT, Ungchusri E, Bercu Z. (April, 2020).
    "Impact of Biodesign Hackathon on Trainee Interest in Interventional Radiology."
    Poster accepted at: Association of University Radiologists 68th Annual Meeting; Philadelphia, PA, USA. Cancelled due to COVID-19.
    https://www.aur.org/en/annual-meeting/archives/2020-annual-meeting

  4. Le RT, Ungchusri E, Li H, Yoon J, Bercu Z, Kwon YJ. (January, 2020).
    "Innovation via the Interwebs - Feasibility of Biodesign Curriculum and Hackathon for Trainee Outreach."
    Poster presented at International Symposium on Endovascular Therapy; Hollywood, FL, USA.
    https://www.vasculardiseasemanagement.com/index.php/abstract/innovation-interwebs-feasibility-biodesign-curriculum-and-hackathon-trainee-outreach

  5. Ranade A, Marinelli B, Kwon YJ, Patel R, Fischman A, Nowakowski F, Lookstein R, Bishay V, Kim E, Ranade M. (March, 2019).
    "Transplenic Access for Transjugular Intrahepatic Portosystemic Shunting: Safety and Feasibility."
    Poster presented at: Society of Interventional Radiology 44th Annual Scientific Meeting; Austin, TX, USA.
    https://www.jvir.org/article/S1051-0443(18)32463-1/fulltext

  6. Falk MJ, Peng M, Kwon YJ, Ostrovsky J, Polyak E, Dugar S, Schreiner G. (March, 2014).
    "(+) Epicatechin therapy has beneficial effects in human cell and C. elegans models of primary mitochondrial respiratory chain disease."
    Poster presented at: Society for Inherited Metabolic Disorders 37th Annual Meeting; Pacific Grove, CA, USA.
    https://www.simd.org/Meetings/SIMD2014/Posters.asp

Patents

  1. Backeris P, Yaeger K, Costa A, Oxley T, Berenstein A, Kwon YJ, Borrello J.
    “Detachable-Tip Balloon Microcatheter for Embolization of Vascular Pathology.”
    U.S. Provisional Pat. Ser. No. 62/799,409, World Intellectual Property Organization WO2020160469A1, published August 8, 2020.

Non Peer-Reviewed Articles

  1. Kwon YJ, Posham R, Patel RS, Fischman A (November, 2018).
    "Predictions for Transradial Access Capabilities in the Near Future."
    Endovascular Today.